Advan. Physiol. Edu. 27: 244-a-245-a, 2003;
doi:10.1152/advan.00021.2003
1043-4046/03 $5.00
ADV PHYSIOL EDUC 27:244-245, 2003
© 2003 American Physiological Society
ILLUMINATION
Pressure-Volume Curve and Compliance of a Balloon: a Simulation
Sarah Weissenberg and
Revital Lavy
The Open University of Israel, PO Box 39328, Tel-Aviv, Israel 61392. E-mail: saraw{at}openu.ac.il
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Abstract
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As educators, we are continually designing new methods and procedures to enhance learning. During this process, good ideas are frequently generated and tested, but the extent of such activities may not be adequate for a full manuscript. Nonetheless, the ideas may be quite beneficial in improving the teaching and learning of physiology. Illuminations is a column designed to facilitate the sharing of these ideas (illuminations). The format of submissions is quite simple: a succinct description of about one or two double-spaced pages (less title and authorship) of something you have used for the classroom, teaching, lab, conference room, etc. You may include one or two simple figures or references. Submit ideas for inclusion in Illuminations directly to the Associate Editor in charge, Stephen DiCarlo (sdicarlo@med.wayne.edu).
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Introduction
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Compliance is a term that is being used in physiology of the respiratory and cardiovascular systems. From our experience, although compliance has rather a simple physical (mathematical) definition, the physiological concept is not so simple and is not intuitively understood by students.
The balloon model is often used in the literature to explain lung (or blood vessels) compliance (1, 2, 3). During their physiology studies, biology undergraduate students do not have the opportunity to measure real lung or blood vessel compliance. Measuring the compliance of a balloon instead may help students to understand the concept better.
Because the Open University is a long-distance learning university, we have prepared a simulation that enables the students to perform the experiment on their home PCs.
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Study Goals
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After the exercise students should be able to- draw a pressure-volume curve of the balloon on the basis of the data they collect.
- calculate the compliance of the balloon from the pressure-volume curve.
- suggest a way to measure compliance of lungs.
- explain the difference between the balloon model and the lung/chest.
- suggest methods to measure compliance of blood vessels.
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Experiment and Simulation
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The simulation is based on a "real" experiment that was performed at the Open University students laboratory with simple equipment: a mercury manometer and a device for measuring the volume of a balloon. To measure the balloons volume, the balloon was immersed in a measuring tube filled with water. The volume change was calculated from the waters height (Archimedes Law). From the data, the volume-pressure curves for inflating and for deflating the balloon were plotted. With a few assumptions, (neglecting the water pressure on the balloon) the balloons compliance can be calculated from the curve. The simulation was prepared by the multimedia team of SHOHAM, The Open University Center for Information Technology in Distance Education.
The simulation can be performed online on the course home page, or it can be downloaded to PCs in the students home. On the simulation (Fig. 1), the students are required to inflate and deflate a virtual balloon and collect the volume and pressure data onto an Excell worksheet. They are asked to draw the pressure-volume curve of the balloon and calculate the compliance.
The simulation is accompanied by a guide and an online multiple-choice preparatory questionnaire. The guide includes theoretical background, instructions for performing the experiment/simulation, and instructions for calculations and lab report. At the end, they have to submit a lab report.
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Acknowledgments
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We thank R. Levin (students lab, Open University of Israel) for assisting with the experiment, Dr. A. Bar-Ilan [The Open University of Israel (current address: QBI Enterprises Ltd., Israel)], and Dr. R. Arieli (Israel Naval Medical Institute) for their advice, and the SHOHAM (Center for Information Technology in Distance Education, The Open University of Israel) multimedia team.
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References
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- Berne RM and Levy MN. Principles of Physiology (3rd ed.). St. Louis, MO: Mosby, chapt. 21, p. 238, 2000.
- DiCarlo SE, Collins HL, and Rodenbaugh DW. Experiment to help students understand pulmonary compliance. Adv Physiol Educ 26: 135136, 2002.[Free Full Text]
- Rhoads R and Pflanzer R. Human Physiology (4th ed.). Belmont, CA: Brooks-Cole, chapt. 20, p. 646, 2003.
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Copyright © 2003 by the American Physiological Society.