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Advan. Physiol. Edu. 32: 120-126, 2008; doi:10.1152/advan.90111.2008
1043-4046/08 $8.00
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ADV PHYSIOL EDUC 32:120-126, 2008
© 2008 American Physiological Society

STAYING CURRENT

Skeletal muscle and bone: effect of sex steroids and aging

Marybeth Brown

Center for Gender Physiology, Physical Therapy Program, Biomedical Sciences, University of Missouri, Columbia, Missouri

Address for reprint requests and other correspondence: M. Brown, Physical Therapy Program, School of Health Professions, 106 Lewis Hall, Columbia, MO 65211 (e-mail: brownmb{at}health.missouri.edu)

Abstract

Both estrogen and testosterone are present in males and females. Both hormones contribute to the well being of skeletal muscle and bone in men and women, and there is evidence that the loss of sex hormones is associated with the age-related decline in bone and skeletal muscle mass. Hormonal supplementation of older adults to restore estrogen and testosterone levels to those of young men and women is not without penalty.

Key words: estrogen; testosterone






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