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Advan. Physiol. Edu. 276: 19S-22S, 1999;
1043-4046/99 $5.00
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Vol. 276, Issue 6, S19-S22, 6-1-99

A LABORATORY DEMONSTRATION FOR LEARNING ABOUT MAST CELL DEGRANULATION

Josá Corado, and Antonio Eblen-Zajjur

A simple experimental model of cell degranulation was implemented that exposed mast cells obtained from Sprague-Dawley rats to saponin. The model is flexible, easy, and low cost, is not very time-consuming to run, and needs a minimum of laboratory resources. It has been used for the last three years in our undergraduate medical physiology courses and has replaced the classic utilization of slides and drawings.







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